To estimate the number of personal Gmail users in the US, I would start by considering the total US population and then segmenting it. I'd begin with the US population (around 330 million) and subtract individuals unlikely to use Gmail, such as young children and potentially some elderly individuals. Then, I'd estimate the percentage of the remaining population that uses email and, within that group, the proportion that uses Gmail. This would involve making assumptions about market share, considering that Gmail is a dominant player but faces competition from other providers like Outlook and Yahoo, as well as integrated services like Apple's iCloud. I would also consider that some users might have multiple email accounts. My estimate would likely fall in the range of 150-200 million personal Gmail users, acknowledging the significant penetration of Google services in the US.