Profluent careers

Profluent is hiring: 12 open roles as of November 13, 2026, 25% remote, 50% of them senior level. Posted pay runs $155k–$339k. The roles ask most for Python, Figma and model evaluation.

AI & machine learning 4 Research & science 4 Software engineering 3 Design & research 1

Which of Profluent’s 12 roles fit you?

Pick your team. landed reads each role against your resume and applies to the ones that fit.

AI & machine learning · 4 open Research & science · 4 open Software engineering · 3 open Design & research · 1 open

Scientist II, Molecular FunctionEmeryville
Machine Learning Scientist, Biomolecular Structure PredictionEmeryville
Scientist II, ScreeningEmeryville
Creative Director Remote
Intern, Software EngineeringEmeryville

See which fit you10 free applications · No card

Profluent is an AI-first protein design company that develops deep generative models to design and validate novel, functional proteins.

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Profluent is inAI native companies Artificial intelligence Generative AI

Open roles

Founded

2022

Headcount

Remote roles

25%

Hiring now · checked today

Profluent has 12 roles open right now.

landed applies to the ones that fit you on Profluent's own site, the hour they go live.

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Scientist II, Molecular Function

Emeryville, California, United States; On-site

Submitted

Machine Learning Scientist, Biomolecular Structure Prediction

Emeryville, California, United States

Applying

Scientist II, Screening

Emeryville, California, United States; On-site

Queued

12 open

Open roles at Profluent

Checked on Profluent’s careers page Nov 13, 2026

Scientist II, Molecular Function

Profluent

Emeryville, California, United States; On-site

Scientist II, Molecular Function

Emeryville, California, United States; On-site

$155k–$160k

1w ago

Machine Learning Scientist, Biomolecular Structure Prediction

Profluent

Emeryville, California, United States

Machine Learning Scientist, Biomolecular Structure Prediction

Emeryville, California, United States

$212k–$339k

1w ago

Scientist II, Screening

Profluent

Emeryville, California, United States; On-site

Scientist II, Screening

Emeryville, California, United States; On-site

$144k–$160k

4w ago

Creative Director

Profluent

Emeryville, California, United States; Hybrid (2-3 days on-site); Remote

Creative Director

Emeryville, California, United States; Hybrid (2-3 days on-site); Remote

$157k–$207k

6w ago

Intern, Software Engineering

Profluent

Emeryville, California, United States

Intern, Software Engineering

Emeryville, California, United States

Pay not posted

6w ago

Intern, Computational Research

Profluent

Emeryville, California, United States; Hybrid (2-3 days on-site)

Intern, Computational Research

Emeryville, California, United States; Hybrid (2-3 days on-site)

Pay not posted

6w ago

Senior Research Associate - Technology Development

Profluent

Emeryville, California, United States; On-site

Senior Research Associate - Technology Development

Emeryville, California, United States; On-site

$104k–$110k

7w ago

Senior IT Operations Engineer

Profluent

Emeryville, California, United States; Hybrid (2-3 days on-site)

Senior IT Operations Engineer

Emeryville, California, United States; Hybrid (2-3 days on-site)

$167k–$206k

8w ago

Apply to Profluent with landed

Profluent hires through Greenhouse. landed applies on Profluent’s own Greenhouse form, with your résumé tailored and every question answered for the role.

1Add your résumé and the roles you want
2landed picks the Profluent roles that fit you
3It applies on Greenhouse. Review each one first if you like

Start free: 10 applications How landed applies on Greenhouse

Posted pay

Profluent salary by role

Across Profluent’s postings that list pay, the middle of the range runs $155k–$339k. The highest posted range right now is $268k–$355k for Director, Software and Data Engineering. Ranges are base pay as the company posts it.

Role	Postings with pay	Posted range
Director, Software and Data Engineering	1	$268k–$355k
Machine Learning Scientist, Biomolecular Structure Prediction	1	$212k–$339k
Software Engineer, Machine Learning Platform	1	$212k–$339k
Machine Learning Scientist, Pretraining	1	$212k–$339k
Machine Learning Scientist, BioML	1	$212k–$339k
Creative Director	1	$157k–$207k
Senior IT Operations Engineer	1	$167k–$206k
Scientist II, Molecular Function	1	$155k–$160k

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Frequently asked

Is Profluent hiring right now?

Yes. Profluent has 12 open roles live on its own careers page today, and the list above refreshes daily.

Does Profluent hire remote?

About 25% of Profluent’s open roles are remote. The rest are based in its offices, including Emeryville, US.

What does Profluent pay?

Across the Profluent postings that list pay, the middle of the range runs $155k–$339k.

How do I apply to Profluent?

Profluent takes applications on Greenhouse. Every role above links to Profluent’s own application. Or let landed apply for you: it fills the company’s form with your profile and writes the answers for each role.